Therapeutic Drug Monitoring - Newer Drugs and Biomarkers (Relié)

Therapeutic Drug Monitoring : Newer Drugs and Biomarkers provides integrated and comprehensive coverage of pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This book offers an objective look into the advances and challenges in the field, including the limitations of current commercially available immunoassays for therapeutic monitoring, new and sophisticated techniques used for proper determination of blood levels, and the clinical utility of therapeutic drug monitoring of both contemporary and more established drugs.
Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential reference on the current practice of therapeutic drug monitoring. Key features : Offers practical and up-to-date information on the monitoring of newer drugs and highlights the role of therapeutic drug monitoring in improving patient safety ; Addresses both the technical and clinical issues associated with therapeutic drug monitoring ; Discusses emerging and specialized topics such as the clinical effectiveness of newer antiretroviral agents, anticonvulsants and antidepressants, drug testing in pain management, dosage adjustments based on computer modeling using pharmacokinetic and pharmacodynamic data, and much more ; Features challenges in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants.